JUP/gamma Catenin Rabbit Polyclonal Antibody
No Size Price Availability  
YRP01725-01 50ul 1500.00 In Stock
YRP01725-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3728
Isotype: IgG Swiss Prot: P14923
purity: Purified by Protein A.
Background:
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Cateninma gamma
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym DP3, PDGB, PKGB, CTNNG, DPIII, ARVD12, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP
This product is for research use only, not for diagnostic or therapeutic use!

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