

| Source: | Rabbit | Gene Id: | 1489088 |
| Isotype: | IgG | Swiss Prot: | P06463 |
| purity: | Purified by Protein A. |
| Background: |
| Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation. |
| Reactivity | Virus (HPV16/HPV18) |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | synthetic peptide from HPV16 E6 + HPV18 E6 conjugated to KLH |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Protein E6, E6 |
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