CD2AP Rabbit Polyclonal Antibody
No Size Price Availability  
YRP00517-01 50ul 1500.00 In Stock
YRP00517-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 23607
Isotype: IgG Swiss Prot: Q9Y5K6
purity: Purified by Protein A.
Background:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human CD2AP
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym CMS, CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
This product is for research use only, not for diagnostic or therapeutic use!

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