
| Source: | Rabbit | Gene Id: | 14082 | 
| Isotype: | IgG | Swiss Prot: | Q61160 | 
| purity: | Purified by Protein A. | 
| Background: | 
| Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    
                                    
                                    
                                    
                                    
                                    
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| Immunogen | KLH conjugated synthetic peptide derived from mouse FADD | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1 | 
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