| No | Size | Price | Availability | |
| YRP00463-01 | 50ul | 1500.00 | In Stock |  |
| YRP00463-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7295 |
| Isotype: | IgG | Swiss Prot: | P10599 |
| purity: | Purified by Protein A. |
| Background: |
| Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Thioredoxin |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | TRX, TRDX, TRX1, Thioredoxin, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN |
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