| No | Size | Price | Availability | |
| YRP13283-01 | 50ul | 1500.00 | In Stock |  |
| YRP13283-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2593 |
| Isotype: | IgG | Swiss Prot: | Q14353 |
| purity: | Purified by Protein A. |
| Background: |
| In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human GAMT |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | PIG2, CCDS2, TP53I2, HEL-S-20, Guanidinoacetate N-methyltransferase, GAMT |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
