GCP3/Gamma-tubulin complex component 3 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP13282-01 50ul 1500.00 In Stock
YRP13282-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 10426
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The Gamma-Tubulin complex is composed of Gamma Tubulin and the Gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. Gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the Gamma-Tubulin complex. GCP3 (Gamma-Tubulin complex component 3), also known as TUBGCP3 or SPBC98, localizes to the centrosome and is a ubiquitously expressed 907 amino acid member of the Gamma-Tubulin complex. Like GCP2 and Gamma Tubulin, GCP3 is conserved in all eukaryotes, suggesting that it is part of a core unit involved in eukaryotic microtubule nucleation. Three isoforms of GCP3 exist due to alternative splicing events.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human GCP3/Gamma-tubulin complex component 3
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Gamma-ring complex protein 104 kDa, Gamma-tubulin complex component 3, GCP-3, GCP3, GCP3_HUMAN, h104p, hGCP3, hGrip104, hSpc98, SPBC98, Spc98p, Spindle pole body protein Spc98 homolog, TUBGCP3, Tubulin gamma complex associated protein 3.
This product is for research use only, not for diagnostic or therapeutic use!

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