| No | Size | Price | Availability | |
| YRP13246-01 | 50ul | 1500.00 | In Stock |  |
| YRP13246-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2767 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Ga subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gq class includes G alpha 15, G alpha 14, G alpha 11 and G alpha q, two of which, G alpha 11 and G alphaq, are abundant in brain and lung and present at lower levels in a variety of tissues (6). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human GNA11 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | G alpha-11, G-protein subunit alpha-11, GNA11, GNA11_HUMAN, Guanine nucleotide-binding protein Gy subunit alpha, Guanine nucleotide-binding protein subunit alpha-11. |
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