HIRA Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7290-01 50ul 1500.00 In Stock
ARP7290-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7290
Isotype: IgG Swiss Prot: P54198
purity: Affinity purification
Background:
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 112kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human HIRA
Storage Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym TUP1, DGCR1, TUPLE1
This product is for research use only, not for diagnostic or therapeutic use!

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