| No | Size | Price | Availability | |
| ARP4653-01 | 50ul | 1500.00 | In Stock |  |
| ARP4653-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4653 |
| Isotype: | IgG | Swiss Prot: | Q99972 |
| purity: | Affinity purification |
| Background: |
| Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893; 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622). MYOC has a molecular weight of 55-57 kDa, besides, a 66-kDa form, which could be a result of post-translational modifications, has also been reported in some researches (PMID: 9497363; 12150989). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 57kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | Recombinant protein of human MYOC |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | GPOA, JOAG, TIGR, GLC1A, JOAG1, myocilin |
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