| No | Size | Price | Availability | |
| ARP7443-01 | 50ul | 1500.00 | In Stock |  |
| ARP7443-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7443 |
| Isotype: | IgG | Swiss Prot: | Q99986 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 45 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | Recombinant protein of human VRK1 |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | PCH1, PCH1A |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
