Source: | Rabbit | Gene Id: | 7430 |
Isotype: | IgG | Swiss Prot: | P15311 |
purity: | Affinity purification |
Background: |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 81 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
ICC 1:50-1:100
FC 1:20-1:50
|
Immunogen | Recombinant protein of human EZR |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CVL, CVIL, VIL2, HEL-S-105 |
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