| No | Size | Price | Availability | |
| ARP50617-01 | 50ul | 1500.00 | In Stock |  |
| ARP50617-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 50617 |
| Isotype: | IgG | Swiss Prot: | Q9HBG4 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 96 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | Recombinant protein of human ATP6V0A4 |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | A4, STV1, VPH1, VPP2, RTA1C, RTADR, ATP6N2, RDRTA2, ATP6N1B |
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