Source: | Rabbit | Gene Id: | 50484 |
Isotype: | IgG | Swiss Prot: | Q7LG56 |
purity: | Affinity purification |
Background: |
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 41 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:50-1:100
|
Immunogen | Recombinant protein of human RRM2B |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | P53R2, MTDPS8A, MTDPS8B |
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