| No | Size | Price | Availability | |
| ARP3757-01 | 50ul | 1500.00 | In Stock |  |
| ARP3757-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3757 |
| Isotype: | IgG | Swiss Prot: | Q12809 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 90 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | Synthetic Peptide of human KCNH2 |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | ERG1, HERG, LQT2, SQT1, ERG-1, H-ERG, HERG1, Kv11.1 |
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