| No | Size | Price | Availability | |
| ARP4001-31 | 50ul | 1500.00 | In Stock |  |
| ARP4001-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4001 |
| Isotype: | IgG | Swiss Prot: | P20700 |
| purity: | Affinity purification |
| Background: |
| The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 66 kDa |
| Recommended Dilutions |
WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
|
| Immunogen | A recombinant protein of human LMNB1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | LMN, ADLD, LMN2, LMNB |
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