| No | Size | Price | Availability | |
| ARP7010P-21 | 50ul | 1500.00 | In Stock |  |
| ARP7010P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7010 |
| Isotype: | / | Swiss Prot: | Q02763 |
| purity: | Affinity purification |
| Background: |
| The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008] |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser1119 of human Tie2 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CD202B, TIE-2, TIE2, VMCM, VMCM1 |
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