| No | Size | Price | Availability | |
| ARP5591P-21 | 50ul | 1500.00 | In Stock |  |
| ARP5591P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5591 |
| Isotype: | / | Swiss Prot: | P78527 |
| purity: | Affinity purification |
| Background: |
| The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 450 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues surrounding Ser2056 of human DNA-PK protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
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