| No | Size | Price | Availability | |
| ARPF026-21 | 50ul | 1500.00 | In Stock |  |
| ARPF026-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2767 2776 2781 |
| Isotype: | / | Swiss Prot: | P29992 P50148 P19086 |
| purity: | Affinity purification |
| Background: |
| Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3). |
| Reactivity | Bovine, Human, Monkey, Mouse, Rat |
| Tested applications | WB IHC IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 39, 41 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:100
|
| Immunogen | A synthetic peptide corresponding to residues of human guanine nucleotide-binding protein Gα (q) subunit |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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