| No | Size | Price | Availability | |
| ARP6622-21S | 50ul | 1500.00 | In Stock |  |
| ARP6622-21S | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6622 |
| Isotype: | / | Swiss Prot: | P37840 |
| purity: | Affinity purification |
| Background: |
| α-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 18 kDa |
| Recommended Dilutions |
WB 1:1000
IF 1:50
|
| Immunogen | A synthetic peptide corresponding to the carboxy terminus of mouse synuclein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | TLR7-like, MGC110988, NACP, PARK1, PARK4, PD1 |
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