Source: | Rabbit | Gene Id: | 182 |
Isotype: | / | Swiss Prot: | P78504 |
purity: | Affinity purification |
Background: |
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq |
Reactivity | Dog, Human, Xenopus |
Tested applications | WB IHC ELISA IF |
Clonality | Polyclonal Antibody |
Calculated MW | 180 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:100-1:500
IF 1:200-1:1000
|
Immunogen | A synthetic peptide corresponding to amino acids 110-125 of human JAG1 |
Storage | Store at 4°C. For long term storage store at -20°C in 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles. |
Synonym | AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644 |
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