| No | Size | Price | Availability | |
| ARP9262-11 | 50ul | 1500.00 | In Stock |  |
| ARP9262-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9262 |
| Isotype: | / | Swiss Prot: | O94768 |
| purity: | Affinity purification |
| Background: |
| DRAK2 (DAP kinase related apoptosis inducing protein kinase 2) is a member of the novel DAP (death associated protein) pro-apoptotic kinase family (1). Overexpression of DRAK2 in NIH/3T3 cells induces morphological changes associated with apoptosis, which are likely to occur in a p53-dependent manner (1,2). DRAK2 is preferentially expressed in lymphoid tissues and regulates the TCR activation threshold during thymocyte selection (3). Indeed, T cells from DRAK2(-/-) mice exhibit enhanced sensitivity to T cell receptor-mediated stimulation and have a reduced requirement for co-stimulation (4). |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 43 kDa |
| Recommended Dilutions |
WB 0.5-1 ug/mL
|
| Immunogen | A synthetic peptide corresponding to amino acids 351-365 of human STK17B |
| Storage | Store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | DRAK2 |
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