| Source: | Rabbit | Gene Id: | 5058/5062 |
| Isotype: | / | Swiss Prot: | Q13153/Q13177 |
| purity: | Protein A purification |
| Background: |
| PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | ELISA Dot |
| Clonality | Polyclonal Antibody |
| Calculated MW | 61-74 kDa |
| Recommended Dilutions |
Dot 1:500
|
| Immunogen | A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T423 of human PAK1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | MGC130000, MGC130001, PAKalpha |
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