| No | Size | Price | Availability | |
| ARP29881-11 | 50ul | 1500.00 | In Stock |  |
| ARP29881-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 29881 |
| Isotype: | IgG | Swiss Prot: | Q9UHC9 |
| purity: | Antigen affinity purification |
| Background: |
| Niemann-Pick C1-like 1 (NPC1L1) is a transmembrane protein that plays a critical role in cholesterol absorption (1). It is highly expressed in small intestine and localized along the brush border in both human and mouse epithelial cells (2,3). NPC1L1 mediates cholesterol uptake via vesicular endocytosis (4). Ezetimibe, a potent cholesterol absorption inhibitor used to treat hypercholesterolemia (5), inhibits cholesterol uptake by preventing NPC1L1 from incorporating into clathrin-coated vesicles (4). |
| Reactivity | Human |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 140 kDa |
| Recommended Dilutions |
IHC 1:20-1:50
|
| Immunogen | A recombinant protein corresponding to amino acids of human NPC1L1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | / |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
