| Source: | Rabbit | Gene Id: | 57446 | 
| Isotype: | IgG | Swiss Prot: | Q9UGV2 | 
| purity: | Antigen affinity purification | 
| Background: | 
| The NDRG (N-Myc downstream-regulated gene) family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis (1-3). NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice (1). Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors (4,5). | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 45 kDa | 
| Recommended Dilutions | 
                                     WB 1:250-1:500 
                                    IHC 1:20-1:50 
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A recombinant protein corresponding to amino acids of human NDRG3 | 
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. | 
| Synonym | FLJ13556 | 
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