| No | Size | Price | Availability | |
| AGP2746-11 | 50ul | 1500.00 | In Stock |  |
| AGP2746-11 | 100ul | 2000.00 | In Stock | |
| Source: | Goat | Gene Id: | 2746 |
| Isotype: | / | Swiss Prot: | P00367 |
| purity: | Antigen affinity purification |
| Background: |
| This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 52 kDa |
| Recommended Dilutions |
WB 0.1-0.3 ug/mL
IHC 3-5 ug/mL
|
| Immunogen | A synthetic peptide corresponding to internal region of human GLUD1/GLUD2 |
| Storage | Store at -20°C in 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles. |
| Synonym | GDH, GDH1, GLUD, MGC132003 |
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