| Source: | Goat | Gene Id: | 5454 | 
| Isotype: | / | Swiss Prot: | P20265 | 
| purity: | Antigen affinity purification | 
| Background: | 
| POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB ELISA | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 55 kDa | 
| Recommended Dilutions | 
                                     WB 0.1-0.3 ug/mL 
                                    
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A synthetic peptide corresponding to amino acids at N-terminus of human POU3F2 | 
| Storage | Store at -20°C in 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles. | 
| Synonym | BRN2, OCT7, OTF7, POUF3 | 
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