Source: | Goat | Gene Id: | 5454 |
Isotype: | / | Swiss Prot: | P20265 |
purity: | Antigen affinity purification |
Background: |
POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM |
Reactivity | Human, Mouse, Rat |
Tested applications | WB ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 55 kDa |
Recommended Dilutions |
WB 0.1-0.3 ug/mL
|
Immunogen | A synthetic peptide corresponding to amino acids at N-terminus of human POU3F2 |
Storage | Store at -20°C in 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles. |
Synonym | BRN2, OCT7, OTF7, POUF3 |
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