| Source: | Rabbit | Gene Id: | 1058 | 
| Isotype: | / | Swiss Prot: | P49450 | 
| purity: | Affinity purification | 
| Background: | 
| Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq | 
| Reactivity | Human | 
| Tested applications | IHC ELISA IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 17 kDa | 
| Recommended Dilutions | 
                                    
                                     IHC 1:50-1:100 
                                    IF 1:500-1:1000 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | A synthetic peptide corresponding to human CENPA | 
| Storage | Store at -20°C in PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. | 
| Synonym | CENP-A | 
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