Source: | Rabbit | Gene Id: | 1058 |
Isotype: | / | Swiss Prot: | P49450 |
purity: | Affinity purification |
Background: |
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq |
Reactivity | Human |
Tested applications | IHC ELISA IF |
Clonality | Polyclonal Antibody |
Calculated MW | 17 kDa |
Recommended Dilutions |
IHC 1:50-1:100
IF 1:500-1:1000
|
Immunogen | A synthetic peptide corresponding to human CENPA |
Storage | Store at -20°C in PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Synonym | CENP-A |
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