| Source: | Rabbit | Gene Id: | 6271 |
| Isotype: | / | Swiss Prot: | P23297 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ELISA IP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 12 kDa |
| Recommended Dilutions |
WB 0.1-1 ug/mL
IHC 1:300
|
| Immunogen | A recombinant protein corresponding to human S100A1 |
| Storage | Store at 4°C. For long term storage store at -20°C or lower in PBS, pH 7.2 (10% Proclin300).Avoid freeze/thaw cycles. |
| Synonym | S100, S100-alpha, S100A |
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