Source: | Rabbit | Gene Id: | 8660 |
Isotype: | / | Swiss Prot: | Q9Y4H2 |
purity: | Affinity purification |
Background: |
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC ELISA IP |
Clonality | Polyclonal Antibody |
Calculated MW | 185 kDa |
Recommended Dilutions |
WB 0.1-1 ug/mL
IHC 0.5-2 ug/mL
|
Immunogen | A synthetic peptide corresponding to residues surrounding S731 of human IRS2 |
Storage | Store at 4°C. For long term storage store at -20°C in TBS, pH 7.2 (10% Proclin300).Avoid freeze/thaw cycles. |
Synonym | / |
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