| No | Size | Price | Availability | |
| ARP5727-11 | 50ul | 1500.00 | In Stock |  |
| ARP5727-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5727 |
| Isotype: | / | Swiss Prot: | Q13635 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC ELISA ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 180-210 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:500-1:1000
ICC 1:500-1:1000
|
| Immunogen | A synthetic peptide corresponding to amino acids 269-279 of human and mouse PTCH1/Ptch1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | BCNS, FLJ26746, FLJ42602, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11 |
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