| Source: | Rabbit | Gene Id: | 1956/2064 |
| Isotype: | / | Swiss Prot: | P00533/P04626 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 185 kDa |
| Recommended Dilutions |
WB 1:1800
|
| Immunogen | A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding EGFR (Y1173)/ERBB2 (Y1248) of human |
| Storage | Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | ERBB, ERBB1, HER1, PIG61, mENA |
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