| Source: | Rabbit | Gene Id: | 10972 |
| Isotype: | / | Swiss Prot: | P49755 |
| purity: | Affinity purification |
| Background: |
| This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq |
| Reactivity | Bovine, Human, Mouse, Primates, Rabbit, Rat, Xenopus |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 19 kDa |
| Recommended Dilutions |
WB 2 ug/mL
IHC 1 ug/mL
|
| Immunogen | A synthetic peptide corresponding to amino acids 50-150 of human TMED10 |
| Storage | Store at -20°C or -80°C in PBS .Avoid freeze/thaw cycles. |
| Synonym | P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I |
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