Source: | Rabbit | Gene Id: | 65266 |
Isotype: | / | Swiss Prot: | Q96J92 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 135-140 kDa |
Recommended Dilutions |
WB 2 ug/mL
|
Immunogen | A synthetic peptide corresponding to amino acids 200-300 of human WNK4 |
Storage | Store at -20°C or -80°C in PBS.Avoid freeze/thaw cycles. |
Synonym | PHA2B, PRKWNK4 |
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