| No | Size | Price | Availability | |
| ARP2736-11 | 50ul | 1500.00 | In Stock |  |
| ARP2736-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2736 |
| Isotype: | / | Swiss Prot: | P10070 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq |
| Reactivity | Bovine, Human, Mouse, Rat |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 220 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:500-1:2000
|
| Immunogen | A synthetic peptide corresponding to amino acids 46-60 of human GLI2 |
| Storage | Store at 4°C. For long term storage store at -20°C in 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | HPE9, THP1, THP2 |
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