Source: | Rabbit | Gene Id: | 10413 |
Isotype: | / | Swiss Prot: | P46937 |
purity: | Affinity purification |
Background: |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
Reactivity | Human |
Tested applications | ELISA Dot |
Clonality | Polyclonal Antibody |
Calculated MW | 65 to 75 kDa |
Recommended Dilutions | |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | AP, YAP2, YAP65, YKI |
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