| No | Size | Price | Availability | |
| ARP2316P-31 | 50ul | 1500.00 | In Stock |  |
| ARP2316P-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2316 |
| Isotype: | / | Swiss Prot: | P21333 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene |
| Reactivity | Human |
| Tested applications | ELISA Dot |
| Clonality | Polyclonal Antibody |
| Calculated MW | 280 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic phosphopeptides corresponding to residues surrounding Ser2152 of human filamin A and Ser2146 of human filamin C |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ABP-280, ABPX, DKFZp434P031, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2 |
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