| No | Size | Price | Availability | |
| ARP27040P-31 | 50ul | 1500.00 | In Stock |  |
| ARP27040P-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 27040 |
| Isotype: | / | Swiss Prot: | O43561 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 36, 38 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic phosphopeptide corresponding to residues around Tyr191 of human LAT |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | LAT1, pp36 |
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