| Source: | Rabbit | Gene Id: | 23118 | 
| Isotype: | / | Swiss Prot: | Q9NYJ8 | 
| purity: | Peptide affinity purification | 
| Background: | 
| The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq | 
| Reactivity | Human | 
| Tested applications | IHC ELISA | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 80 kDa | 
| Recommended Dilutions | 
                                    
                                     IHC 5 ug/mL 
                                    
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | A synthetic peptide corresponding to 14 amino acids at C-terminus of human MAP3K7IP2 | 
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. | 
| Synonym | FLJ21885, KIAA0733, TAB2 | 
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.