| Source: | Rabbit | Gene Id: | 1051 |
| Isotype: | / | Swiss Prot: | Q13131P54646 |
| purity: | Antigen affinity purification |
| Background: |
| The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 62 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide corresponding to human PRKAA1/PRKAA2 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2 (0.05% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | AMPK, AMPKa1, MGC33776, MGC57364 |
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