| No | Size | Price | Availability | |
| ARP321-13 | 50ul | 1500.00 | In Stock |  |
| ARP321-13 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 321 |
| Isotype: | / | Swiss Prot: | Q99767 |
| purity: | Affinity purification |
| Background: |
| Amyloid β A4 precursor protein-binding family A member 2 (APBA2) is a neuronal adaptor protein that interacts with the amyloid β precursor protein (APP) (1). The amyloid β-protein (Aβ) is the principal component of amyloid plaques, a pathological hallmark of Alzheimer’s disease (2). APBA2 has been shown to stabilize APP metabolism and suppress the secretion of Aβ (3). APBA2 mediates interaction between APP and the neural type I membrane protein Alcadein (Alc) by linking their cytoplasmic domains, thereby forming a tripartite complex of the three proteins in neurons (4). |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 135 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
IHC 10 ug/mL
|
| Immunogen | A synthetic peptide corresponding to 18 amino acids near internal region of human APBA2 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FLJ25458, FLJ37160, GIDRP86, PSORT |
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