| No | Size | Price | Availability | |
| ARP60673-11 | 50ul | 1500.00 | In Stock |  |
| ARP60673-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 60673 |
| Isotype: | / | Swiss Prot: | Q9BSB4 |
| purity: | Affinity purification |
| Background: |
| Atg101 was discovered as a binding protein for Atg13, a component of the ULK1 serine-threonine kinase complex required for autophagy (1-3). Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (4,5). It is generally activated by conditions of nutrient deprivation, but is also associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer (6). The molecular machinery of autophagy was largely discovered in yeast and is directed by a number of autophagy-related (Atg) genes. The ULK1 complex includes both Atg13 and FIP200 and is required for starvation-induced autophagy (7-9). Interaction between Atg101 and Atg13 can be important for the stability and basal phosphorylation of Atg13 and ULK1 (1,2). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 25 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
IHC 5 ug/mL
|
| Immunogen | A synthetic peptide corresponding to 16 amino acids near internal region of human C12orf44 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FLJ11773 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
