Source: | Rabbit | Gene Id: | 1365 |
Isotype: | IgG | Swiss Prot: | O15551 |
purity: | Affinity purification |
Background: |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 23 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of human CLDN3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5629% glycerol. Avoid freeze/thaw cycles. |
Synonym | RVP1,HRVP1,C7orf1,CPE-R2,CPETR2 |
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