| No | Size | Price | Availability | |
| ARP2925-61 | 50ul | 1500.00 | In Stock |  |
| ARP2925-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2925 |
| Isotype: | IgG | Swiss Prot: | P30550 |
| purity: | Affinity purification |
| Background: |
| Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 43 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
| Immunogen | A recombinant protein of human GRPR |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5907% glycerol. Avoid freeze/thaw cycles. |
| Synonym |
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