Source: | Rabbit | Gene Id: | 2833 |
Isotype: | IgG | Swiss Prot: | P49682 |
purity: | Affinity purification |
Background: |
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 46 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of human CXCR3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5948% glycerol. Avoid freeze/thaw cycles. |
Synonym | GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R |
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