
| Source: | Rabbit | Gene Id: | 115426 | 
| Isotype: | IgG | Swiss Prot: | Q96PU4 | 
| purity: | Affinity purification | 
| Background: | 
| This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012] | 
| Reactivity | Human | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 90 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50 | 
| Immunogen | A recombinant protein of human UHRF2 | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | NIRF, URF2, RNF107, RP11-472F14.2 | 
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