| No | Size | Price | Availability | |
| ARP29128-61 | 50ul | 1500.00 | In Stock |  |
| ARP29128-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 29128 |
| Isotype: | IgG | Swiss Prot: | Q96T88 |
| purity: | Affinity purification |
| Background: |
| UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2. |
| Reactivity | Human |
| Tested applications | WB IHC IF IP ChIP |
| Clonality | Polyclonal Antibody |
| Calculated MW | 91 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:20-1:50
ChIP 1:20-1:50
|
| Immunogen | A recombinant protein of human UHRF1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95 |
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