Adracalin Rabbit Polyclonal Antibody
No Size Price Availability  
YRP11812-01 50ul 1500.00 In Stock
YRP11812-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id:
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Adracalin
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym AAA, AAAS, AAASb, Achalasia adrenocortical insufficiency alacrimia Allgrove triple A, Achalasia adrenocortical insufficiency alacrimia, ADRACALA, Aladin, Allgrove triple A, DKFZp586G1624, GL003, AAAS_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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