RAPGEF5 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP9771-61 50ul 1500.00 In Stock
ARP9771-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 9771
Isotype: IgG Swiss Prot: Q92565
purity: Affinity purification
Background:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 60 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym GFR, guanine nucleotide exchange factor for Rap1, M-Ras-regulated GEF, M-Ras-regulated Rap GEF, MR-GEF, MRGEF, RPGF5
This product is for research use only, not for diagnostic or therapeutic use!

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