| No | Size | Price | Availability | |
| ARP4926-61 | 50ul | 1500.00 | In Stock |  |
| ARP4926-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4926 |
| Isotype: | IgG | Swiss Prot: | Q14980 |
| purity: | Affinity purification |
| Background: |
| The nuclear mitotic apparatus protein (NuMA) is a coiled coil protein involved in the formation and maintenance of the mitotic spindle. NuMA plays a role in chromatin organization during interphase, which influences mammary epithelial differentiation (1,2). During apoptosis, carboxy-terminal cleavage of NuMA may amplify signaling in the cell death pathway (2). NuMA is phosphorylated at numerous sites, with phosphorylation at Ser395 occurring in an ATM/ATR-dependent manner in response to DNA damage (3,4). |
| Reactivity | Human |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 240 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Nuclear mitotic apparatus protein 1, NuMA protein, SP-H antigen |
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